Rufinamide-d2

• CAT Number: S000439
• CAS Number: 1129491-38-8
• Molecular Formula: C10H6D2F2N4O
• Molecular Weight: 240.21
• Purity: ≥95%
• IUPAC Name: 1-[dideuterio-(2,6-difluorophenyl)methyl]triazole-4-carboxamide
• InChI: InChI=1S/C10H8F2N4O/c11-7-2-1-3-8(12)6(7)4-16-5-9(10(13)17)14-15-16/h1-3,5H,4H2,(H2,13,17)/i4D2
• InChIKey: POGQSBRIGCQNEG-APZFVMQVSA-N
• SMILES: C1=CC(=C(C(=C1)F)CN2C=C(N=N2)C(=O)N)F

Rufinamide-d2（Cat No.:S000439） is a deuterated version of rufinamide, where two hydrogen atoms are replaced with deuterium. This modification improves the compound’s stability, making it particularly useful for pharmacokinetic and metabolic studies. Rufinamide is an anticonvulsant drug used primarily to treat seizures associated with Lennox-Gastaut syndrome, a severe form of childhood epilepsy. It works by stabilizing sodium channels in the brain, reducing neuronal excitability, and preventing seizure propagation. The deuterated version, Rufinamide-d2, provides researchers with a tool to investigate how the drug is metabolized and to potentially enhance its efficacy and safety profile.