Ruxotemitide (LTX 315)

• CAT Number: I047448
• CAS Number: 1345407-05-7
• Molecular Formula: C78H106N18O9
• Molecular Weight: 1439.79
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)C(C(=O)NC(CCCCN)C(=O)N)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CNC8=CC=CC=C87)NC(=O)C(CCCCN)NC(=O)C(CCCCN)N

Ruxotemitide (LTX 315) is the oncolytic peptide that kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization.

Reference

[1] Camilio KA ,et al. Oncoimmunology. 2014, 3: e29181.
[2] Paal Brunsvig, et al. J Clin Oncol.2014, 32:5s.