For research use only. Not for therapeutic Use.
RV-1729(Cat No.:I008850)is a synthetic small molecule being explored for its potential therapeutic applications, particularly in the field of oncology. It is known for its ability to inhibit certain protein kinases that regulate cell growth, survival, and proliferation. By targeting these signaling pathways, RV-1729 may help slow down or stop the growth of cancer cells, making it a promising candidate for cancer treatment. Research is ongoing to assess its efficacy in preclinical models, and its safety and potential as a treatment for various cancers are being evaluated in clinical studies.
Catalog Number | I008850 |
CAS Number | 1293915-42-0 |
Synonyms | RV-1729; RV 1729; RV1729;6-(2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-3-(2-chlorobenzyl)-4-oxo-3,4-dihydroquinazolin-5-yl)-N,N-bis(2-methoxyethyl)hex-5-ynamide |
Molecular Formula | C39H39ClN8O5 |
Purity | ≥95% |
Target | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase (PI3K) Inhibitor |
Solubility | Soluble in DMSO |
Storage | Store at -20°C |
IUPAC Name | 6-[2-[[4-amino-3-(3-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-3-[(2-chlorophenyl)methyl]-4-oxoquinazolin-5-yl]-N,N-bis(2-methoxyethyl)hex-5-ynamide |
InChI | InChI=1S/C39H39ClN8O5/c1-52-20-18-46(19-21-53-2)33(50)17-5-3-4-10-26-12-9-16-31-34(26)39(51)47(23-28-11-6-7-15-30(28)40)32(44-31)24-48-38-35(37(41)42-25-43-38)36(45-48)27-13-8-14-29(49)22-27/h6-9,11-16,22,25,49H,3,5,17-21,23-24H2,1-2H3,(H2,41,42,43) |
InChIKey | UBLOHCIYTDRGJH-UHFFFAOYSA-N |
SMILES | COCCN(CCOC)C(=O)CCCC#CC1=C2C(=CC=C1)N=C(N(C2=O)CC3=CC=CC=C3Cl)CN4C5=NC=NC(=C5C(=N4)C6=CC(=CC=C6)O)N |