For research use only. Not for therapeutic Use.
RY796 is a potent and selective voltage-gated potassium (KV2) channel inhibitor with IC50s of 0.25 μM and 0.09 μM for KV2.1 and KV2.2. RY796 has analgesic activity[1].
| Catalog Number | I009245 |
| CAS Number | 1393441-53-6 |
| Synonyms | 2-(dimethylamino)-5-(2-methylpropanoylamino)-N-[(1R)-1-phenylethyl]benzamide |
| Molecular Formula | C21H27N3O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H27N3O2/c1-14(2)20(25)23-17-11-12-19(24(4)5)18(13-17)21(26)22-15(3)16-9-7-6-8-10-16/h6-15H,1-5H3,(H,22,26)(H,23,25)/t15-/m1/s1 |
| InChIKey | LDXZFQWWXMRMAS-OAHLLOKOSA-N |
| SMILES | CC(C)C(=O)NC1=CC(=C(C=C1)N(C)C)C(=O)NC(C)C2=CC=CC=C2 |
| Reference | [1]. Herrington J, et al. Identification of novel and selective Kv2 channel inhibitors. Mol Pharmacol. 2011 Dec;80(6):959-64. |
