For research use only. Not for therapeutic Use.
Ryanodine(CAT: R014100) is a plant alkaloid that is well-known for its potent effects on calcium ion channels, particularly the ryanodine receptor (RyR) in muscle cells. By binding to these receptors, ryanodine plays a critical role in modulating calcium release from the sarcoplasmic reticulum, which is essential for muscle contraction. Ryanodine has been extensively studied in both skeletal and cardiac muscle physiology for its ability to alter calcium dynamics, influencing muscle function. It is also used as a research tool to study calcium signaling, excitation-contraction coupling, and associated disorders like malignant hyperthermia and cardiac arrhythmias.
| Catalog Number | R014100 |
| CAS Number | 15662-33-6 |
| Synonyms | Ryanodol, 3-(1H-pyrrole-2-carboxylate); (+)-Ryanodine; [3S-(3α,4β,4aS*,6α,6aα,7α,8β,8aα,8bβ,9β,9aα)]-Dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethyl-7-(1-methylethyl)-6,9-methanobenzo[1,2]pentaleno[1,6-bc]furan-8-yl Ester 1H-Pyrrole-2-carbox |
| Molecular Formula | C25H35NO9 |
| Purity | ≥95% |
| Target | Disease Research Fields |
| Solubility | Soluble in DMSO > 10 mM |
| Storage | Desiccate at -20C |
