For research use only. Not for therapeutic Use.
Very potent and selective 5-HT1A agonist
| Catalog Number | I009248 |
| CAS Number | 135722-25-7 |
| Molecular Formula | C24H26FN3O2 |
| Purity | ≥95% |
| IUPAC Name | 4-fluoro-N-[2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl]benzamide |
| InChI | InChI=1S/C24H26FN3O2/c1-30-21-10-7-18-3-2-4-23(22(18)17-21)28-15-13-27(14-16-28)12-11-26-24(29)19-5-8-20(25)9-6-19/h2-10,17H,11-16H2,1H3,(H,26,29) |
| SMILES | COC1=CC2=C(C=CC=C2N3CCN(CC3)CCNC(=O)C4=CC=C(C=C4)F)C=C1 |
| Reference | G Milligan et al. S 14506: novel receptor coupling at 5-HT1A receptors. Neuropharmacology. 2001, 40, 334.
AJ Goudie. Assessment of the dependence potential of the potent high-efficacy 5-HT1A agonist S-14506 in rats. J Psychopharmacol. 1994, 8(4), 213-221.
FC Colpaert et al. S 14506: A novel, potent, high-efficacy 5-HT1A agonist and potential anxiolytic agent. Drug Develop. Res. 1992, 26(1), 21–48. |
