(S)-4-Carboxyphenylglycine

• CAT Number: I010191
• CAS Number: 134052-73-6
• Molecular Formula: C9H9NO4
• Molecular Weight: 195.17
• Purity: ≥95%
• Synonyms: Alternative Name: (S)-4CPG
• Target: Neuronal Signaling
• Solubility: Soluble to 100 mM in 1eq. NaOH with gentle warming
• Storage: Store at RT
• IUPAC Name: 4-[(S)-amino(carboxy)methyl]benzoic acid
• InChI: InChI=1S/C9H9NO4/c10-7(9(13)14)5-1-3-6(4-2-5)8(11)12/h1-4,7H,10H2,(H,11,12)(H,13,14)/t7-/m0/s1
• InChIKey: VTMJKPGFERYGJF-ZETCQYMHSA-N
• SMILES: C1=CC(=CC=C1C(C(=O)O)N)C(=O)O

(S)-4-Carboxyphenylglycine(CAT: I010191) is a selective antagonist of group I metabotropic glutamate receptors (mGluRs), specifically mGluR1 and mGluR5, widely utilized in neuroscience research. This compound plays a significant role in studying glutamatergic neurotransmission, synaptic plasticity, and excitotoxicity. Its inhibitory activity provides insights into the pathological mechanisms underlying neurological disorders such as epilepsy, neurodegenerative diseases, and chronic pain. With high purity and stability, (S)-4-Carboxyphenylglycine is ideal for in vitro and in vivo applications, supporting the development of therapeutic strategies targeting glutamate-mediated signaling pathways in the central nervous system.