(S)-ARI-1

• CAT Number: I040082
• CAS Number: 2003228-82-6
• Molecular Formula: C20H22O7
• Molecular Weight: 374.38
• Purity: ≥95%
• Synonyms: (2S)-5,7-bis(methoxymethoxy)-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one
• InChI: InChI=1S/C20H22O7/c1-22-11-25-15-8-18(26-12-23-2)20-16(21)10-17(27-19(20)9-15)13-4-6-14(24-3)7-5-13/h4-9,17H,10-12H2,1-3H3/t17-/m0/s1
• InChIKey: PUZCVJRGJCUWMV-KRWDZBQOSA-N
• SMILES: COCOC1=CC2=C(C(=O)CC(O2)C3=CC=C(C=C3)OC)C(=C1)OCOC

(S)-ARI-1 (Cat No.: I040082) is a selective small-molecule inhibitor designed for cancer and inflammation research. It targets key signaling pathways involved in cell proliferation, immune modulation, and tumor progression, making it a valuable tool for drug discovery and mechanistic studies. With high bioavailability and specificity, (S)-ARI-1 is optimized for in vitro and in vivo applications, ensuring reliable results in oncology, immunology, and metabolic disease research. Its well-defined structure enhances stability and potency, supporting the development of next-generation targeted therapies.

Reference

[1]. Xuesha Liu, et al. Novel ROR1 inhibitor ARI-1 suppresses the development of non-small cell lung cancer. Cancer Lett. 2019 Aug 28:458:76-85.
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