(S)-ARI-1

• CAT Number: I040082
• CAS Number: 2003228-82-6
• Molecular Formula: C20H22O7
• Molecular Weight: 374.38
• Purity: ≥95%
• Synonyms: (2S)-5,7-bis(methoxymethoxy)-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one
• InChI: InChI=1S/C20H22O7/c1-22-11-25-15-8-18(26-12-23-2)20-16(21)10-17(27-19(20)9-15)13-4-6-14(24-3)7-5-13/h4-9,17H,10-12H2,1-3H3/t17-/m0/s1
• InChIKey: PUZCVJRGJCUWMV-KRWDZBQOSA-N
• SMILES: COCOC1=CC2=C(C(=O)CC(O2)C3=CC=C(C=C3)OC)C(=C1)OCOC

(S)-ARI-1 is an S-enantiomer of ARI-1. ARI-1 is a ROR1 inhibitor and apoptosis inducer, used in NSCLC research[1].

Reference

[1]. Xuesha Liu, et al. Novel ROR1 inhibitor ARI-1 suppresses the development of non-small cell lung cancer. Cancer Lett. 2019 Aug 28:458:76-85.
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