For research use only. Not for therapeutic Use.
Equol ,a metabolite of soybeans, is an important isoflavone in humans，specifically binds to 5α-DHT, has a modest affinity for recombinant estrogen receptor ERβ. Phase 2.<br>Equol is a metabolite produced from the soy phytoestrogen daidzein by the action of gut microflora. Equol has higher affinity for both ERs (estrogen receptors including ERalpha and ERbeta). Equol exists as the enantiomers R-equol and S-equol. S-equol has a high binding affinity, preferential for ERbeta with a K<sub>i</sub> of 16 nM whereas R-equol binds more weakly and with a preference for ERalpha K with a K<sub>i</sub> of 50 nM.
| Catalog Number | R006446 |
| CAS Number | 531-95-3 |
| Synonyms | (S)-3-(4-Hydroxy-phenyl)-chroman-7-ol; (S)-3,4-Dihydro-3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol; 3-(4-Hydroxy-phenyl)-chroman-7-ol; (-)-Equol; (S)-(-)-4’,7-Isoflavandiol; |
| Molecular Formula | C15H14O3 |
| Purity | ≥95% |
| Documentation | |
| Target | Metabolic Enzyme/Protease |
| Solubility | >12.1mg/mL in DMSO |
| Storage | 3 years -20C powder |
| InChIKey | ADFCQWZHKCXPAJ-GFCCVEGCSA-N |
