For research use only. Not for therapeutic Use.
(S)-ErSO is the dextrorotatory enantiomer of ErSO. (S)-ErSO is inactive in MCF-7 cells (from patent WO2020009958A1, compound (s)-105)[1].
(-)-ErSO induces dose-dependent death of MCF-7 cells. (+)-l05 is inactive[1].
| Catalog Number | I045396 |
| CAS Number | 2407860-34-6 |
| Synonyms | (3S)-3-(4-hydroxyphenyl)-3-[4-(trifluoromethoxy)phenyl]-7-(trifluoromethyl)-1H-indol-2-one |
| Molecular Formula | C22H13F6NO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C22H13F6NO3/c23-21(24,25)17-3-1-2-16-18(17)29-19(31)20(16,12-4-8-14(30)9-5-12)13-6-10-15(11-7-13)32-22(26,27)28/h1-11,30H,(H,29,31)/t20-/m0/s1 |
| InChIKey | ZFSRXAHDJSCEDS-FQEVSTJZSA-N |
| SMILES | C1=CC2=C(C(=C1)C(F)(F)F)NC(=O)C2(C3=CC=C(C=C3)O)C4=CC=C(C=C4)OC(F)(F)F |
| Reference | [1]. David J. Shapiro, et al. Activators of the unfolded protein response. WO2020009958A1. |
