(S)-FTY720-phosphonate

• CAT Number: R027801
• CAS Number: 1142015-10-8
• Molecular Formula: C20H36NO4P
• Molecular Weight: 385.48
• Purity: ≥95%
• Synonyms: [(3S)-3-amino-3-(hydroxymethyl)-5-(4-octylphenyl)pentyl]phosphonic acid
• InChI: InChI=1S/C20H36NO4P/c1-2-3-4-5-6-7-8-18-9-11-19(12-10-18)13-14-20(21,17-22)15-16-26(23,24)25/h9-12,22H,2-8,13-17,21H2,1H3,(H2,23,24,25)/t20-/m0/s1
• InChIKey: XDSPSYJWGHPIAZ-FQEVSTJZSA-N
• SMILES: CCCCCCCCC1=CC=C(C=C1)CC[C@](CCP(=O)(O)O)(CO)N

(S)-FTY720-phosphonate（Cat No.:R027801）is a potent sphingosine-1-phosphate (S1P) receptor modulator and a phosphorylated derivative of FTY720 (fingolimod). It acts by binding to S1P receptors, leading to the internalization of lymphocytes and inhibiting their migration, which is particularly beneficial in autoimmune diseases like multiple sclerosis. (S)-FTY720-phosphonate has been shown to modulate immune cell trafficking, reducing inflammation and tissue damage. This compound is being studied for its potential in treating autoimmune conditions, preventing transplant rejection, and other diseases where immune cell activation plays a significant role in pathogenesis.