(S)-Higenamine

• CAT Number: I015304
• CAS Number: 22672-77-1
• Molecular Formula: C₁₆H₁₇NO₃
• Molecular Weight: 271.31
• Purity: ≥95%
• Target: Endogenous Metabolite
• IUPAC Name: (1S)-1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
• InChI: InChI=1S/C16H17NO3/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14/h1-4,8-9,14,17-20H,5-7H2/t14-/m0/s1
• InChIKey: WZRCQWQRFZITDX-AWEZNQCLSA-N
• SMILES: C1CN[C@H](C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O

(S)-Higenamine（Cat No.:I015304）is a naturally occurring alkaloid found in several plant species, including Nandina domestica (sacred bamboo). It is known for its stimulating effects, as it acts as a β2-adrenergic receptor agonist, promoting bronchodilation and increasing heart rate. Due to these properties, (S)-higenamine has been explored for its potential use as a treatment for asthma, as well as for enhancing athletic performance by increasing energy expenditure and fat oxidation. However, its safety and efficacy, particularly in athletic supplements, remain under investigation, and its use may be subject to regulatory scrutiny.

Reference

[1]. Minami H, et al. Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem. 2007;282(9):6274‐6282.