(S)-(+)-Ibuprofen-d3

• CAT Number: R046278
• CAS Number: 1329643-44-8
• Molecular Formula: C13H18O2
• Molecular Weight: 209.303
• Purity: ≥95%
• Synonyms: (αS)-α-(Methyl-d3)-4-(2-methylpropyl)benzeneacetic Acid; (+)-Ibuprofen-d3; (S)-2-(4-Isobutylphenyl)propanoic Acid-d3; (S)-Ibuprofen-d3; S-(+)-p-Isobutylhydratropic Acid-d3
• Target: COX
• Storage: -20°C
• IUPAC Name: (2S)-3,3,3-trideuterio-2-[4-(2-methylpropyl)phenyl]propanoic acid
• InChI: InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m0/s1/i3D3
• InChIKey: HEFNNWSXXWATRW-PCXQMPHHSA-N
• SMILES: [2H]C([2H])([2H])[C@@H](C1=CC=C(C=C1)CC(C)C)C(=O)O

(S)-(+)-Ibuprofen-d3 is a deuterated form of the (S)-(+)-enantiomer of ibuprofen, with three hydrogen atoms replaced by deuterium. This isotopically labeled compound is crucial in pharmacokinetic and metabolic studies, allowing for precise tracking and analysis without altering the drug’s therapeutic activity. (S)-(+)-Ibuprofen is the active enantiomer responsible for the anti-inflammatory, analgesic, and antipyretic effects of ibuprofen, commonly used to treat pain, inflammation, and fever. In pharmaceutical research, (S)-(+)-Ibuprofen-d3 helps in studying drug metabolism, interaction, and absorption in the body.