(S)-Indoximod-d3

• CAT Number: S000489
• CAS Number: 1801851-87-5
• Molecular Formula: C12H11D3N2O2
• Molecular Weight: 221.27
• Purity: ≥95%
• IUPAC Name: (2S)-2-amino-3-[1-(trideuteriomethyl)indol-3-yl]propanoic acid
• InChI: InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m0/s1/i1D3
• InChIKey: ZADWXFSZEAPBJS-ASGODXDTSA-N
• SMILES: CN1C=C(C2=CC=CC=C21)CC(C(=O)O)N

(S)-Indoximod-d3（Cat No.:S000489） is a deuterated form of (S)-Indoximod, where three hydrogen atoms are replaced with deuterium. (S)-Indoximod is an immunomodulatory agent that inhibits the enzyme indoleamine 2,3-dioxygenase (IDO), which is involved in tumor immune resistance. By blocking IDO, (S)-Indoximod enhances the immune system’s ability to attack cancer cells. The inclusion of deuterium in (S)-Indoximod-d3 increases the compound’s metabolic stability, facilitating more accurate pharmacokinetic and pharmacodynamic studies.