For research use only. Not for therapeutic Use.
(S)-Lisofylline ((S)-Lisophylline)) is a kind of lisofline (LSF) enantiomer with optical activity. (S)-Lisofylline can interconversion with pentoxifylline[1][2].
(S)-Lisofylline ((S)-Lisophylline) can interconversion with pentoxifylline in human hemolytic erythrocytes[2].
(S)-Lisofylline (50 mg/kg; i.v.; single dose) shows higher content in liver, kidney and lung of mice, but lower in serum[2].
| Catalog Number | M132280 |
| CAS Number | 100324-80-9 |
| Synonyms | 1-[(5S)-5-hydroxyhexyl]-3,7-dimethylpurine-2,6-dione |
| Molecular Formula | C13H20N4O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3/t9-/m0/s1 |
| InChIKey | NSMXQKNUPPXBRG-VIFPVBQESA-N |
| SMILES | CC(CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C)O |
| Reference | [1]. Borowiecki P, et al. Chemoenzymatic deracemization of lisofylline catalyzed by a (laccase/TEMPO)-alcohol dehydrogenase system[J]. Catalysis Science & Technology, 2022, 12(13): 4312-4324. [2]. Wyska E, et al. Interconversion and tissue distribution of pentoxifylline and lisofylline in mice. Chirality. 2006 Aug;18(8):644-51. |
