S-Nitroso-N-acetyl-D,L-penicillamine

• CAT Number: R000326
• CAS Number: 67776-06-1
• Molecular Formula: C7H12N2O4S
• Molecular Weight: 220.243
• Purity: ≥95%
• Synonyms: SNAP; N-(Acetyl)-3-(nitrosothio)valine
• Target: NO Synthase
• Storage: -20°C
• IUPAC Name: 2-acetamido-3-methyl-3-nitrososulfanylbutanoic acid
• InChI: InChI=1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)
• InChIKey: ZIIQCSMRQKCOCT-UHFFFAOYSA-N
• SMILES: CC(=O)NC(C(=O)O)C(C)(C)SN=O

SNAP is an S-<wbr></wbr>nitrosothiol which serves as a NO donor and a potent vasodilator. Its stability in solution varies from seconds to hours depending on temperature, buffer composition and metal content. At pH 6-<wbr></wbr>8 and 37°C, the half-<wbr></wbr>life of SNAP is approximately six hours in the presence of transition metal ion chelators.