(S)-Norfluoxetine-d5(Phenyl-d5)

• CAT Number: R012301
• CAS Number: 1217770-71-2
• Molecular Formula: C16H16F3NO
• Molecular Weight: 300.336
• Purity: ≥95%
• Synonyms: (γS)-γ-[4-(Trifluoromethyl)phenoxy](benzene-d5)propanamine; ?(S)-3-(4-Trifluoromethylphenoxy)-3-(phenyl-d5)propylamine; Seproxetine-d5; ?
• Storage: -20°C
• IUPAC Name: (3S)-3-(2,3,4,5,6-pentadeuteriophenyl)-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
• InChI: InChI=1S/C16H16F3NO/c17-16(18,19)13-6-8-14(9-7-13)21-15(10-11-20)12-4-2-1-3-5-12/h1-9,15H,10-11,20H2/t15-/m0/s1/i1D,2D,3D,4D,5D
• InChIKey: WIQRCHMSJFFONW-KPSZHSGHSA-N
• SMILES: C1=CC=C(C=C1)C(CCN)OC2=CC=C(C=C2)C(F)(F)F

(S)-Norfluoxetine-d5 (Phenyl-d5) is a deuterated form of (S)-norfluoxetine, the active metabolite of the antidepressant fluoxetine (commonly known as Prozac). In this compound, five hydrogen atoms in the phenyl ring are replaced with deuterium. This isotopic labeling makes it particularly useful in pharmacokinetic and metabolic studies, enabling precise tracking and analysis in mass spectrometry and NMR spectroscopy. The deuterium substitution helps distinguish the labeled compound from its non-labeled counterpart without altering its pharmacological activity, making it valuable for detailed research into the drug’s metabolism and effects.