(S)-Norketamine hydrochloride

• CAT Number: I011378
• CAS Number: 83777-70-2
• Molecular Formula: C12H15Cl2NO
• Molecular Weight: 260.158
• Purity: ≥95%
• Synonyms: (S)-2-Amino-2-(2-chlorophenyl)cyclohexan-1-one hydrochloride
• IUPAC Name: (2S)-2-amino-2-(2-chlorophenyl)cyclohexan-1-one;hydrochloride
• InChI: InChI=1S/C12H14ClNO.ClH/c13-10-6-2-1-5-9(10)12(14)8-4-3-7-11(12)15;/h1-2,5-6H,3-4,7-8,14H2;1H/t12-;/m0./s1
• InChIKey: CLPOJGPBUGCUKT-YDALLXLXSA-N
• SMILES: C1CCC(C(=O)C1)(C2=CC=CC=C2Cl)N.Cl

NMDA receptor modulator. Metabolite of Ketamine hydrochloride. Decreases intracellular D-serine concentration (IC50 = 62.4 nM) and alters serine racemase expression in PC-12 cells. Exhibits analgesic effects in rat pain models.