(S)-SKBG-1

• CAT Number: I047710
• CAS Number: 2955618-24-1
• Molecular Formula: C22H26ClN3O6S
• Molecular Weight: 495.98
• Purity: ≥95%
• IUPAC Name: (2S)-4-(2-chloroacetyl)-N-[(4-methoxyphenyl)methyl]-1-(4-methoxyphenyl)sulfonylpiperazine-2-carboxamide
• InChI: InChI=1S/C22H26ClN3O6S/c1-31-17-5-3-16(4-6-17)14-24-22(28)20-15-25(21(27)13-23)11-12-26(20)33(29,30)19-9-7-18(32-2)8-10-19/h3-10,20H,11-15H2,1-2H3,(H,24,28)/t20-/m0/s1
• SMILES: COC1=CC=C(C=C1)CNC(=O)[C@@H]2CN(CCN2S(=O)(=O)C3=CC=C(C=C3)OC)C(=O)CCl

Inactive enantiomer of (R)-SKBG-1 (Axon 3928) which is a covalent RNA-binding protein NONO ligand.
Keywords: (S)-SKBG-1 | Supplier | NONO ligand | (S)-SKBG1 | (S)-SKBG 1 | CAS [2955618-24-1] | Androgenic hormones | Androgen (AR) | Inactive | Receptors | RNA-binding protein NONO | RBP | non-POU domain-containing octamer binding | Inactive control

Reference

SG Kathman et al. Remodeling oncogenic transcriptomes by small molecules targeting NONO. Nat Chem Biol. 2023 Jul;19(7):825-836.