For research use only. Not for therapeutic Use.
(S)-Tenofovir(Cat No.:R017842)is the stereoisomeric form of Tenofovir, a nucleoside reverse transcriptase inhibitor (NRTI) used in the treatment of HIV and chronic hepatitis B. It is a potent antiviral agent that works by inhibiting the reverse transcription of viral RNA into DNA, a key step in viral replication. The (S)-enantiomer of Tenofovir is preferred for its higher efficacy and better pharmacokinetic profile compared to the racemic mixture. It is used in combination with other antiretroviral drugs to improve treatment outcomes and reduce viral load in infected patients.
Catalog Number | R017842 |
CAS Number | 147127-19-3 |
Synonyms | P-[[(1S)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-phosphonic Acid; (S)-9-(2-Phosphonomethoxypropyl)adenine; (S)-PMPA |
Molecular Formula | C9H14N5O4P |
Purity | ≥95% |
Target | HIV |
Storage | Store at -20°C |
IUPAC Name | [(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid |
InChI | InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m0/s1 |
InChIKey | SGOIRFVFHAKUTI-LURJTMIESA-N |
SMILES | C[C@@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(O)O |