(S)-TXNIP-IN-1

• CAT Number: I015556
• CAS Number: 1212421-96-9
• Molecular Formula: C12H12N2O4
• Molecular Weight: 248.23
• Purity: ≥95%
• Synonyms: (2S)-2-(1,3-dioxopyrrolo[3,4-c]pyridin-2-yl)-3-methylbutanoic acid
• InChI: InChI=1S/C12H12N2O4/c1-6(2)9(12(17)18)14-10(15)7-3-4-13-5-8(7)11(14)16/h3-6,9H,1-2H3,(H,17,18)/t9-/m0/s1
• InChIKey: KTDYLXVLROCGRL-VIFPVBQESA-N
• SMILES: CC(C)C(C(=O)O)N1C(=O)C2=C(C1=O)C=NC=C2

(S)-TXNIP-IN-1 is the less active S-enantiomer of TXNIP-IN-1 (HY-115688). TXNIP-IN-1 is a TXNIP-TRX complex inhibitor which can be used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease[1]

Reference

[1]. Rama Natarajan, et al. Txnip-trx complex inhibitors and methods of using the same. US20200085800A1.