For research use only. Not for therapeutic Use.
S6K-18 is a potent and selective p70S6K1 inhibitor with an IC50 of 52 nM[1].
| Catalog Number | M141357 |
| CAS Number | 1265789-88-5 |
| Synonyms | 5-tert-butyl-2-(1H-indazol-5-ylcarbamoylamino)thiophene-3-carboxylic acid |
| Molecular Formula | C17H18N4O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C17H18N4O3S/c1-17(2,3)13-7-11(15(22)23)14(25-13)20-16(24)19-10-4-5-12-9(6-10)8-18-21-12/h4-8H,1-3H3,(H,18,21)(H,22,23)(H2,19,20,24) |
| InChIKey | BSRFCMMJUFQEOX-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C1=CC(=C(S1)NC(=O)NC2=CC3=C(C=C2)NN=C3)C(=O)O |
| Reference | [1]. Ye P, et al. Potent and selective thiophene urea-templated inhibitors of S6K. Bioorg Med Chem Lett. 2011 Jan 15;21(2):849-52. |
