SA4503

• CAT Number: I002162
• CAS Number: 165377-43-5
• Molecular Formula: C23H32N2O2
• Molecular Weight: 368.51
• Purity: ≥95%
• Target: Sigma Receptor
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IC50: 17.4 nM [1]
• IUPAC Name: 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine
• InChI: InChI=1S/C23H32N2O2/c1-26-22-11-10-21(19-23(22)27-2)12-14-25-17-15-24(16-18-25)13-6-9-20-7-4-3-5-8-20/h3-5,7-8,10-11,19H,6,9,12-18H2,1-2H3
• InChIKey: UVSWWUWQVAQPJR-UHFFFAOYSA-N
• SMILES: COC1=C(C=C(C=C1)CCN2CCN(CC2)CCCC3=CC=CC=C3)OC

SA4503 (CAT: I002162) is a selective sigma-1 receptor (σ1R) agonist with neuroprotective and neuroregenerative properties. By targeting the σ1R, it modulates calcium signaling, mitochondrial function, and cellular stress responses, making it particularly valuable in neuroscience research. This compound has shown potential in studies on neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, as well as depression and stroke recovery. SA4503 is a critical tool for exploring the therapeutic potential of σ1R modulation and advancing research into treatments for central nervous system disorders.