Sacubitril calcium salt

• CAT Number: I009271
• CAS Number: 1369773-39-6
• Molecular Formula: C48H56CaN2O10
• Molecular Weight: 861.06
• Purity: 98%
• Target: Neprilysin
• Solubility: Soluble in water, Soluble in DMSO.
• Appearance: white to off-white solid powder
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: calcium;4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate
• InChI: InChI=1S/2C24H29NO5.Ca/c2*1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19;/h2*4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28);/q;;+2/p-2/t2*17-,21+;/m11./s1
• InChIKey: DDLCKLBRBPYKQS-OXXXZDCLSA-L
• SMILES: O=C(CCC(N[C@H](CC1=CC=C(C=C1)C2=CC=CC=C2)C[C@H](C(OCC)=O)C)=O)[O-].O=C(CCC(N[C@H](CC3=CC=C(C=C3)C4=CC=CC=C4)C[C@H](C(OCC)=O)C)=O)[O-].[Ca+2]

Sacubitril Calcium Salt(CAT: I009271) is a prodrug and neprilysin inhibitor widely used in cardiovascular research. It plays a pivotal role in studying the regulation of natriuretic peptides, which are essential for vasodilation, diuresis, and counteracting neurohormonal overactivation in heart failure. Sacubitril is particularly valuable for exploring therapeutic strategies in heart failure with reduced ejection fraction (HFrEF). As a key component in combination therapies, it provides insights into enhancing cardiovascular outcomes. With its high purity and relevance, Sacubitril Calcium Salt is a critical tool for advancing research in heart failure management and related cardiovascular disorders.