Sacubitril-d4 hemicalcium salt

• CAT Number: S000458
• Molecular Formula: C24H25D4NO50.5Ca
• Molecular Weight: 435.56
• Purity: ≥95%

A sacubitril-d4 hemicalcium salt（Cat No.:S000458） is a deuterated form of sacubitril, where four hydrogen atoms are replaced with deuterium. This modification is used to enhance the compound’s stability and is pivotal for detailed pharmacokinetic research. Sacubitril is part of the drug combination sacubitril/valsartan, used primarily to treat heart failure. It acts as a neprilysin inhibitor, which increases levels of natriuretic peptides aiding in cardiovascular function improvement by reducing blood pressure and decreasing fluid overload. The deuterated form, Sacubitril-d4 hemicalcium salt, allows researchers to more precisely trace the drug’s metabolic pathways and degradation processes.