For research use only. Not for therapeutic Use.
SAHA chloroalkane T1 is a chloroalkane capture tag by tethering Vorinostat (SAHA) and a chloroalkane tag T1[1].
SAHA chloroalkane T1 minimally affects SAHA potency in K-562 cells, allowing binding interactions with the targets to occur under conditions relevant to the desired cellular phenotype[1].
| Catalog Number | I019275 |
| CAS Number | 1613617-05-2 |
| Synonyms | 2-[2-[2-[[4-[[8-(hydroxyamino)-8-oxooctanoyl]amino]phenyl]methylcarbamoyloxy]ethoxy]ethoxy]ethyl N-[2-[2-(6-chlorohexoxy)ethoxy]ethyl]carbamate |
| Molecular Formula | C33H55ClN4O11 |
| Purity | ≥95% |
| InChI | InChI=1S/C33H55ClN4O11/c34-15-7-3-4-8-17-44-19-20-45-18-16-35-32(41)48-25-23-46-21-22-47-24-26-49-33(42)36-27-28-11-13-29(14-12-28)37-30(39)9-5-1-2-6-10-31(40)38-43/h11-14,43H,1-10,15-27H2,(H,35,41)(H,36,42)(H,37,39)(H,38,40) |
| InChIKey | QJTGTGYXESVKJU-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1CNC(=O)OCCOCCOCCOC(=O)NCCOCCOCCCCCCCl)NC(=O)CCCCCCC(=O)NO |
| Reference | [1]. Ohana RF, et al. Deciphering the Cellular Targets of Bioactive Compounds Using a Chloroalkane Capture Tag. ACS Chem Biol. 2015 Oct 16;10(10):2316-24. |
