SAHM1

For research use only. Not for therapeutic Use.

  • CAT Number: I044302
  • CAS Number: 2050906-89-1
  • Molecular Formula: C94H162N36O23S
  • Molecular Weight: 2196.58
  • Purity: ≥95%
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SAHM1, a peptide mimetic of a dominant negative form of mastermind-like (MAML), inhibits canonical Notch transcription complex formation. SAHM1 can be used for the research of allergic airway inflammation in mice[1][2].


Catalog Number I044302
CAS Number 2050906-89-1
Molecular Formula C94H162N36O23S
Purity ≥95%
Reference

[1]. Ashley JW, et, al. Notch signaling promotes osteoclast maturation and resorptive activity. J Cell Biochem. 2015 Nov;116(11):2598-609.
 [Content Brief]

[2]. KleinJan A, et, al. The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma. J Allergy Clin Immunol. 2018 Jul;142(1):76-85.e8.
 [Content Brief]

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