For research use only. Not for therapeutic Use.
SAHM1, a peptide mimetic of a dominant negative form of mastermind-like (MAML), inhibits canonical Notch transcription complex formation. SAHM1 can be used for the research of allergic airway inflammation in mice[1][2].
Catalog Number | I044302 |
CAS Number | 2050906-89-1 |
Molecular Formula | C94H162N36O23S |
Purity | ≥95% |
Reference | [1]. Ashley JW, et, al. Notch signaling promotes osteoclast maturation and resorptive activity. J Cell Biochem. 2015 Nov;116(11):2598-609. [2]. KleinJan A, et, al. The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma. J Allergy Clin Immunol. 2018 Jul;142(1):76-85.e8. |