For research use only. Not for therapeutic Use.
Salicyl-AMS（Cat No.:I013001）is a chemical compound commonly used in biochemical and pharmaceutical research. It serves as a substrate in enzyme assays, particularly for the study of sulfotransferases and other biotransformation enzymes. The compound is characterized by its ability to undergo sulfation, making it an essential tool for investigating metabolic processes, including drug metabolism and the role of sulfation in detoxification. With high purity and reliability, Salicyl-AMS is ideal for applications in enzyme kinetics, drug interaction studies, and the exploration of sulfation pathways in drug development and safety testing.
| Catalog Number | I013001 |
| CAS Number | 863238-55-5 |
| Molecular Formula | C₁₇H₁₈N₆O₈S |
| Purity | ≥95% |
| Target | Bacterial |
| Solubility | DMSO |
| Storage | Store at -20°C |
| IUPAC Name | [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-(2-hydroxybenzoyl)sulfamate |
| InChI | InChI=1S/C17H18N6O8S/c18-14-11-15(20-6-19-14)23(7-21-11)17-13(26)12(25)10(31-17)5-30-32(28,29)22-16(27)8-3-1-2-4-9(8)24/h1-4,6-7,10,12-13,17,24-26H,5H2,(H,22,27)(H2,18,19,20)/t10-,12-,13-,17-/m1/s1 |
| InChIKey | SABYITLYKSVAAD-CNEMSGBDSA-N |
| SMILES | C1=CC=C(C(=C1)C(=O)NS(=O)(=O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O)O |
| Reference | [1]. Lun S, et al. Pharmacokinetic and in vivo efficacy studies of the mycobactin biosynthesis inhibitor salicyl-AMS in mice. Antimicrob Agents Chemother. 2013 Oct;57(10):5138-40.<br>[2]. Ferreras JA, et al. Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis. Nat Chem Biol. 2005 Jun;1(1):29-32. |
