Salinomycin Sodium

• CAT Number: I004077
• CAS Number: 55721-31-8
• Molecular Formula: C₄₂H₆₉O₁₁. Na
• Molecular Weight: 772.98
• Purity: ≥95%
• Synonyms: sodium;2-[6-[6-[3-(5-ethyl-5-hydroxy-6-methyloxan-2-yl)-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoate
• Target: Antibiotic
• Solubility: DMSO: ≥ 35 mg/mL
• Storage: Store at -20°C
• InChI: InChI=1S/C42H70O11.Na/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33;/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47)
• InChIKey: YPZYGIQXBGHDBH-UZHRAPRISA-M
• SMILES: CCC(C1CCC(C(O1)C(C)C(C(C)C(=O)C(CC)C2C(CC(C3(O2)C=CC(C4(O3)CCC(O4)(C)C5CCC(C(O5)C)(CC)O)O)C)C)O)C)C(=O)[O-].[Na+]

Salinomycin Sodium (CAT: I004077) is a polyether antibiotic that exhibits potent anticancer properties, particularly against cancer stem cells. It is primarily used as an ionophore that disrupts ion homeostasis in cells, leading to various physiological effects. Salinomycin has been shown to selectively target and eliminate cancer stem cells, which are thought to be responsible for tumor initiation, progression, and resistance to therapy. Additionally, salinomycin exhibits antimicrobial activity against certain pathogens, making it useful in veterinary medicine. Its unique mechanism of action and ability to target cancer stem cells make salinomycin a promising candidate for cancer therapy and stem cell research.