Salmeterol

• CAT Number: I005348
• CAS Number: 89365-50-4
• Molecular Formula: C25H37NO4
• Molecular Weight: 415.57
• Purity: ≥95%
• Target: beta2-Adrenergic Receptor
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: 2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol
• InChI: InChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2
• InChIKey: GIIZNNXWQWCKIB-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O

Salmeterol (Cat.No:I005348) is a long-acting beta-2 adrenergic agonist used as a bronchodilator to manage asthma and chronic obstructive pulmonary disease (COPD). It works by relaxing the smooth muscles in the airways, improving airflow and reducing bronchoconstriction. Salmeterol provides sustained relief and is often used in combination with corticosteroids for better asthma control.

Reference

[1]. Rong, Y., et al., Probing the salmeterol binding site on the beta 2-adrenergic receptor using a novel photoaffinity ligand, [(125)I]iodoazidosalmeterol. Biochemistry, 1999. 38(35): p. 11278-86.