For research use only. Not for therapeutic Use.
Salsolidine (CAT: I020248) is a tetrahydroisoquinoline alkaloid that acts as a stereoselective competitive inhibitor of monoamine oxidase A (MAO-A). MAO-A is an enzyme involved in the breakdown of neurotransmitters such as serotonin and norepinephrine. By inhibiting MAO-A, salsolidine can increase the levels of these neurotransmitters, which may have implications for mood regulation and the treatment of certain psychiatric disorders.
| Catalog Number | I020248 |
| CAS Number | 5784-74-7 |
| Molecular Formula | C₁₂H₁₇NO₂ |
| Purity | ≥95% |
| Target | Monoamine Oxidase |
| Reference | [1]. Bembenek ME, et al. Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines. J Med Chem. 1990 Jan;33(1):147-52.<br>[2]. Airaksinen MM, et al. Binding of beta-carbolines and tetrahydroisoquinolines by opiate receptors of the delta-type. Acta Pharmacol Toxicol (Copenh). 1984 Nov;55(5):380-5.<br>[3]. Tundis R, et al. A potential role of alkaloid extracts from Salsola species (Chenopodiaceae) in the treatment of Alzheimer’s disease. J Enzyme Inhib Med Chem. 2009 Jun;24(3):818-24. |
