For research use only. Not for therapeutic Use.
Sancycline hydrochloride（Cat No.:R004759）, is a derivative of tetracycline antibiotics. It is used in the pharmaceutical industry for its antibiotic properties. Sancycline and its hydrochloride salt are employed to combat bacterial infections by inhibiting the growth and replication of bacteria. This compound is effective against a wide range of gram-positive and gram-negative bacteria, making it valuable in the treatment of various bacterial infections. It operates by interfering with the bacteria’s ability to produce essential proteins, thereby stopping their growth. Sancycline hydrochloride plays a crucial role in modern medicine for managing infectious diseases and is an important tool for healthcare.
| Catalog Number | R004759 |
| CAS Number | 6625-20-3 |
| Synonyms | (4S,4aS,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1-11-dioxo-2-naphthacenecarboxamide Hydrochloride; Bonomycin; Norcycline; 6-Demethyl-6-deoxytetracycline Hydrochloride; GS 2147; |
| Molecular Formula | C21H23ClN2O7 |
| Purity | ≥95% |
| Target | Antibiotic |
| Storage | -20°C |
| IUPAC Name | (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride |
| InChI | InChI=1S/C21H22N2O7.ClH/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29;/h3-5,9-10,15,24-25,28,30H,6-7H2,1-2H3,(H2,22,29);1H/t9-,10-,15-,21-;/m0./s1 |
| InChIKey | CIJFGLCHAOVWRZ-QKYUADJBSA-N |
| SMILES | CN(C)C1C2CC3CC4=C(C(=CC=C4)O)C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O.Cl |
| Reference | Process for the catalytic reduction of 6-hydroxynaphthacenes. McCormick J.R.D. & Jensen E.R. 1962 US Patent 3,019,260.<br/><br/>The total synthesis of 6-demethyl-6-deoxytetracycline. Conover L.H. et al. J. Am. Chem. Soc. 1962, 84, 3222.</span></p> |
