For research use only. Not for therapeutic Use.
Sandalore, a synthetic sandalwood odorant, is a selective agonist of the olfactory receptor OR2AT4, thereby inducing the increase of the intracellular Ca2+ and cAMP levels in human keratinocytes. Specific stimulation of OR2AT4 by Sandalore prolongs human hair growth ex vivo by decreasing apoptosis and increasing production of the anagen-prolonging growth factor IGF-1.
KEYWORDS: Sandalore | Supplier | OR2AT4 agonist | CAS [65113-99-7] | Odor molecule | Olfactory Receptor | Agonist | Receptors | Melanoma | Parkinson’s disease | Odorant receptor
| Catalog Number | I047676 |
| CAS Number | 65113-99-7 |
| Molecular Formula | C14H26O |
| Purity | ≥95% |
| IUPAC Name | 3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pentan-2-ol |
| InChI | InChI=1S/C14H26O/c1-10(12(3)15)6-8-13-9-7-11(2)14(13,4)5/h7,10,12-13,15H,6,8-9H2,1-5H3 |
| SMILES | CC1=CCC(C1(C)C)CCC(C)C(C)O |
| Reference | B Pavan et al. Odorants could elicit repair processes in melanized neuronal and skin cells. Neural Regen Res. 2017 Sep;12(9):1401-1404. J Chéret et al. Olfactory receptor OR2AT4 regulates human hair growth. Nat Commun. 2018 Sep 18;9(1):3624. |
