Sanguinarine chloride

• CAT Number: I004081
• CAS Number: 5578-73-4
• Molecular Formula: C20H14NO4 • Cl
• Molecular Weight: 367.8
• Purity: ≥95%
• Synonyms: 13-methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, monochloride
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: 24-methyl-5,7,18,20-tetraoxa-24-azoniahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(24),2,4(8),9,11,13,15,17(21),22-nonaene;chloride
• InChI: InChI=1S/C20H14NO4.ClH/c1-21-8-15-12(4-5-16-20(15)25-10-22-16)13-3-2-11-6-17-18(24-9-23-17)7-14(11)19(13)21;/h2-8H,9-10H2,1H3;1H/q+1;/p-1
• InChIKey: GIZKAXHWLRYMLE-UHFFFAOYSA-M
• SMILES: C[N+]1=C2C(=C3C=CC4=C(C3=C1)OCO4)C=CC5=CC6=C(C=C52)OCO6.[Cl-]

Sanguinarine chloride (Cat.No:I004081) is a natural alkaloid derived from the bloodroot plant (Sanguinaria canadensis). It possesses various biological activities, including antimicrobial, anti-inflammatory, and anticancer properties. Sanguinarine chloride has been studied for its potential in treating oral diseases, skin conditions, and as a potential therapeutic agent against certain cancers.

Reference

[1]. Jamie Rosen, et al. Characterization and Assessment of Nanoencapsulated Sanguinarine Chloride as a Potential Treatment for Melanoma. Journal of drugs in dermatology: JDD (Impact Factor: 1.32). 05/2015; 14(5):453-458.

[2]. Afseth J, et al. Clinical Experiments with a Mouthrinse Containing Sanguinarine Chloride. Caries Res 1987;21:285–288