For research use only. Not for therapeutic Use.
Sappanone A is a homoisoflavanone which exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Sappanone can attenuate allergic airway inflammation in Ovalbumin-induced asthma[1].
| Catalog Number | I045590 |
| CAS Number | 102067-84-5 |
| Synonyms | (3E)-3-[(3,4-dihydroxyphenyl)methylidene]-7-hydroxychromen-4-one |
| Molecular Formula | C16H12O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H12O5/c17-11-2-3-12-15(7-11)21-8-10(16(12)20)5-9-1-4-13(18)14(19)6-9/h1-7,17-19H,8H2/b10-5+ |
| InChIKey | KVYZXXBTJHJISR-BJMVGYQFSA-N |
| SMILES | C1C(=CC2=CC(=C(C=C2)O)O)C(=O)C3=C(O1)C=C(C=C3)O |
| Reference | [1]. Lee S, et, al. Sappanone A exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Int Immunopharmacol. 2015 Sep;28(1):328-36. [2]. Liu X, et, al. Sappanone A Attenuates Allergic Airway Inflammation in Ovalbumin-Induced Asthma. Int Arch Allergy Immunol. 2016;170(3):180-6. |
