[Sar9,Met(O2)11]-Substance P TFA

For research use only. Not for therapeutic Use.

  • CAT Number: I046121
  • CAS Number: 2828433-10-7
  • Molecular Formula: C66H101F3N18O17S
  • Molecular Weight: 1507.68
  • Purity: ≥95%
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[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK1 receptor selective agonist.
[Sar9,Met(O2)11]-Substance P and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P is the sole to produce grooming[1].


Catalog Number I046121
CAS Number 2828433-10-7
Molecular Formula C66H101F3N18O17S
Purity ≥95%
Reference

[1]. Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127(3):717-28.
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