Saracatinib

For research use only, not for therapeutic use.

  • CAT Number: I003391
  • CAS Number: 379231-04-6
  • Molecular Formula: C₂₇H₃₂ClN₅O₅
  • Molecular Weight: 542.03
  • Purity: 98%
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Saracatinib(Cat No.:I003391)is a potent and selective Src kinase inhibitor essential for advanced cancer research. By targeting the Src family of tyrosine kinases, it plays a critical role in studying signal transduction pathways involved in cancer progression and metastasis. This high-purity compound ensures precise and reliable analytical results, making it ideal for experimental setups focused on oncological research and drug development. Its stability and efficacy support robust investigations into novel cancer therapies, offering significant potential in the fight against various malignancies and enhancing the understanding of cancer biology.


Catalog Number I003391
CAS Number 379231-04-6
Synonyms

N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(oxan-4-yloxy)quinazolin-4-amine; Saracatinib (AZD0530)

Molecular Formula C₂₇H₃₂ClN₅O₅
Purity 98%
Target Bcr-Abl
Solubility DMSO: ≥ 44 mg/mL
Storage 3 years -20C powder
IC50 2.7 nM(c-Src); 30 nM (v-Abl)
IUPAC Name N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(oxan-4-yloxy)quinazolin-4-amine
InChI InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)
InChIKey OUKYUETWWIPKQR-UHFFFAOYSA-N
SMILES CN1CCN(CC1)CCOC2=CC3=C(C(=C2)OC4CCOCC4)C(=NC=N3)NC5=C(C=CC6=C5OCO6)Cl

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