For research use only. Not for therapeutic Use.
Sarafloxacin HCl（Cat No.:A000527）is a fluoroquinolone antibiotic developed for veterinary use, primarily to treat bacterial infections in poultry and aquaculture. It functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and repair, leading to cell death. Effective against a range of Gram-negative and some Gram-positive bacteria, sarafloxacin HCl is particularly useful for treating respiratory, enteric, and systemic infections. Due to its targeted efficacy and relatively low risk of resistance development, it is widely applied in veterinary medicine, though it is restricted in food animals in certain regions.
| Catalog Number | A000527 |
| CAS Number | 91296-87-6 |
| Synonyms | A-56620 HCl |
| Molecular Formula | C20H17F2N3O3.HCl |
| Purity | ≥95% |
| Target | Bacterial |
| Storage | 3 years -20C powder |
| IUPAC Name | 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrochloride |
| InChI | InChI=1S/C20H17F2N3O3.ClH/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-16(22)18(10-17(14)25)24-7-5-23-6-8-24;/h1-4,9-11,23H,5-8H2,(H,27,28);1H |
| InChIKey | KNWODGJQLCISLC-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F.Cl |
| Reference | Wolfson, John S., and David C. Hooper. /The Fluoroquinolones: Structures, Mechanisms of Action and Resistance, and Spectra of Activity in Vitro./ American Society for Microbiology 4th ser. 28 (1985): 581-86.</span></p> |
