SARS-CoV-2 nsp14-IN-3

• CAT Number: I040942
• CAS Number: 2920574-16-7
• Molecular Formula: C17H17N3O3S
• Molecular Weight: 343.40
• Purity: ≥95%
• Synonyms: 5-formyl-4-methyl-N-[2-methyl-3-(2-oxoimidazolidin-1-yl)phenyl]thiophene-2-carboxamide
• InChI: InChI=1S/C17H17N3O3S/c1-10-8-14(24-15(10)9-21)16(22)19-12-4-3-5-13(11(12)2)20-7-6-18-17(20)23/h3-5,8-9H,6-7H2,1-2H3,(H,18,23)(H,19,22)
• InChIKey: ZJRJCWRBMHUFCK-UHFFFAOYSA-N
• SMILES: CC1=C(SC(=C1)C(=O)NC2=C(C(=CC=C2)N3CCNC3=O)C)C=O

SARS-CoV-2 nsp14-IN-3 (4975) is an inhibitor of the SARS-CoV-2 Nsp14 N7-Methyltransferase (IC50: 3.5 μM)[1].

Reference

[1]. Singh I, et al. Structure-Based Discovery of Inhibitors of the SARS-CoV-2 Nsp14 N7-Methyltransferase. J Med Chem. 2023 Jun 22;66(12):7785-7803.
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