SB 202190 Hydrochloride

• CAT Number: R054818
• CAS Number: 350228-36-3
• Molecular Formula: C20H15ClFN3O
• Molecular Weight: 367.80
• Purity: ≥95%
• Synonyms: 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol Monohydrochloride
• Target: MAPK/ERK Pathway
• Storage: -20°C
• IUPAC Name: 4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenol;hydrochloride
• InChI: InChI=1S/C20H14FN3O.ClH/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15;/h1-12,25H,(H,23,24);1H
• InChIKey: XOQSUTIMRLPFPB-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)O.Cl

SB 202190 Hydrochloride（Cat No.:R054818）is a potent and selective inhibitor of p38 MAPK, specifically targeting the p38α and p38β isoforms. It is widely used in research to study the role of the p38 MAPK signaling pathway in cellular responses to stress, inflammation, and apoptosis. By inhibiting p38 MAPK, SB 202190 reduces the production of pro-inflammatory cytokines and mediators, making it valuable in exploring treatments for inflammatory diseases, cancer, and neurodegenerative disorders. Its specificity and effectiveness make it a key compound for investigating the therapeutic potential of targeting p38 MAPK.