SB 204144

• CAT Number: I009305
• CAS Number: 141396-10-3
• Molecular Formula: C42H51N4O8P
• Molecular Weight: 770.864
• Purity: ≥95%
• Synonyms: SB 204144; SB204144; SB-204144.;2,5,9,12-Tetraaza-7-phosphatridecanedioic acid, 7-hydroxy-3,11-bis(1-methylethyl)-4,10-dioxo-6,8-bis(phenylmethyl)-, bis(phenylmethyl) ester, 7-oxide, (3S-(3R*,6S*,8S*,11R*))-
• Solubility: Soluble in DMSO
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: bis[(1R)-1-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]-2-phenylethyl]phosphinic acid
• InChI: InChI=1S/C42H51N4O8P/c1-29(2)37(45-41(49)53-27-33-21-13-7-14-22-33)39(47)43-35(25-31-17-9-5-10-18-31)55(51,52)36(26-32-19-11-6-12-20-32)44-40(48)38(30(3)4)46-42(50)54-28-34-23-15-8-16-24-34/h5-24,29-30,35-38H,25-28H2,1-4H3,(H,43,47)(H,44,48)(H,45,49)(H,46,50)(H,51,52)/t35-,36-,37+,38+/m1/s1
• InChIKey: NKLAQVJZOVABOV-RNATXAOGSA-N
• SMILES: CC(C)C(C(=O)NC(CC1=CC=CC=C1)P(=O)(C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)OCC3=CC=CC=C3)O)NC(=O)OCC4=CC=CC=C4

SB 204144 (Cat.No:I009305) is a chemical compound that acts as a selective antagonist of the 5-HT1B receptor, a subtype of serotonin receptors. It has been studied for its potential in the treatment of various neurological and psychiatric disorders, including migraine headaches and depression. SB 204144’s unique pharmacological profile makes it valuable in understanding serotonin receptor function and exploring therapeutic interventions.