SB 205384

• CAT Number: I009308
• CAS Number: 160296-13-9
• Molecular Formula: C17H18N2O3S
• Molecular Weight: 330.40
• Purity: ≥95%
• Synonyms: SB 205384; SB-205384; SB205384.;but-2-yn-1-yl (R)-4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-b]pyridine-3-carboxylate
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO
• Storage: Desiccate at RT
• IUPAC Name: but-2-ynyl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylate
• InChI: InChI=1S/C17H18N2O3S/c1-3-4-7-22-17(21)13-9(2)19-16-14(15(13)18)11-6-5-10(20)8-12(11)23-16/h10,20H,5-8H2,1-2H3,(H2,18,19)
• InChIKey: JDTZAGLGBRRCJT-UHFFFAOYSA-N
• SMILES: CC#CCOC(=O)C1=C(N=C2C(=C1N)C3=C(S2)CC(CC3)O)C

SB 205384（Cat No.:I009308）is a selective inhibitor of the enzyme 5-lipoxygenase (5-LO), which plays a key role in the biosynthesis of leukotrienes, inflammatory mediators involved in asthma, allergy, and other inflammatory conditions. By inhibiting 5-LO, SB 205384 reduces the production of leukotrienes, potentially providing therapeutic benefits in conditions like asthma, chronic obstructive pulmonary disease (COPD), and allergic rhinitis. This compound has been studied for its ability to alleviate symptoms associated with these conditions, such as airway constriction and inflammation. Further clinical research is required to assess its efficacy, safety, and long-term therapeutic potential.