SB-237376 HCl

• CAT Number: I009319
• CAS Number: 179258-62-9 (HCl)
• Molecular Formula: C20H26ClN3O5
• Molecular Weight: 423.89
• Purity: ≥95%
• Synonyms: SB-237376 HCl; SB-237376 hydrochloride; SB-237376; SB 237376; SB237376.;N-(3-((2-(3,4-Dimethoxyphenyl)ethyl)amino)propyl)-4-nitrobenzamide hydrochloride
• Target: potassium channel antagonist
• Solubility: Soluble in DMSO
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: N-[3-[2-(3,4-dimethoxyphenyl)ethylamino]propyl]-4-nitrobenzamide;hydrochloride
• InChI: InChI=1S/C20H25N3O5.ClH/c1-27-18-9-4-15(14-19(18)28-2)10-13-21-11-3-12-22-20(24)16-5-7-17(8-6-16)23(25)26;/h4-9,14,21H,3,10-13H2,1-2H3,(H,22,24);1H
• InChIKey: QLUVAVFNMRXIIZ-UHFFFAOYSA-N
• SMILES: COC1=C(C=C(C=C1)CCNCCCNC(=O)C2=CC=C(C=C2)[N+](=O)[O-])OC.Cl

SB-237376 HCl（Cat No.:I009319）is a chemical compound that functions as a potent and selective inhibitor of the p38 mitogen-activated protein kinase (MAPK) pathway. The p38 MAPK pathway plays a critical role in inflammatory responses, cellular stress, and apoptosis. By inhibiting p38 MAPK, SB-237376 HCl has potential therapeutic applications in treating inflammatory diseases, autoimmune conditions, and certain cancers. The hydrochloride salt form (HCl) enhances its solubility and stability. While primarily used in preclinical research, this compound holds promise for developing therapies targeting p38 MAPK-driven diseases and disorders.