SB-258585 hydrochloride

• CAT Number: I010480
• CAS Number: 1216468-02-8
• Molecular Formula: C18H23ClIN3O3S
• Molecular Weight: 523.82
• Purity: ≥95%
• Synonyms: 4-iodo-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]benzenesulfonamide;hydrochloride
• InChI: InChI=1S/C18H22IN3O3S.ClH/c1-21-9-11-22(12-10-21)17-13-15(5-8-18(17)25-2)20-26(23,24)16-6-3-14(19)4-7-16;/h3-8,13,20H,9-12H2,1-2H3;1H
• InChIKey: BFGOZFXMAJBFGI-UHFFFAOYSA-N
• SMILES: CN1CCN(CC1)C2=C(C=CC(=C2)NS(=O)(=O)C3=CC=C(C=C3)I)OC.Cl

SB-258585 Hydrochloride(CAT: I010480) is a high-affinity, selective antagonist of the 5-HT6 serotonin receptor, which is predominantly expressed in the central nervous system. It is widely used in neuroscience research to study cognitive function, memory, and neuropsychiatric disorders such as Alzheimer’s disease, schizophrenia, and depression. By blocking 5-HT6 receptor activity, SB-258585 modulates neurotransmitter release and synaptic plasticity, offering insights into serotonergic signaling pathways. Supplied as a hydrochloride salt for improved solubility and stability, this compound is a valuable pharmacological tool in both in vitro and in vivo studies.