For research use only. Not for therapeutic Use.
SB-269970 hydrochloride（Cat No.:I002897）is a selective antagonist of the 5-HT7 serotonin receptor, widely used in neuroscience research to explore the role of this receptor in regulating mood, cognition, and circadian rhythms. By blocking 5-HT7 receptor activity, SB-269970 hydrochloride provides insights into potential treatments for psychiatric and neurological disorders, such as depression, anxiety, and schizophrenia. Its high specificity and potency make it an essential tool in studying serotonin-mediated signaling pathways, offering a valuable contribution to the development of novel therapeutics targeting mental health conditions.
| Catalog Number | I002897 |
| CAS Number | 261901-57-9 |
| Synonyms | 3-[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidin-1-yl]sulfonylphenol;hydrochloride |
| Molecular Formula | C18H28N2O3S • HCl |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | DMSO: ≥ 30 mg/mL |
| Storage | 3 years -20C powder |
| IC50 | 8.3 (pKi for 5-HT7) |
| IUPAC Name | 3-[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidin-1-yl]sulfonylphenol;hydrochloride |
| InChI | InChI=1S/C18H28N2O3S.ClH/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18;/h2,5-6,14-16,21H,3-4,7-13H2,1H3;1H/t16-;/m1./s1 |
| InChIKey | XQCJOYZLWFNDIO-PKLMIRHRSA-N |
| SMILES | CC1CCN(CC1)CC[C@H]2CCCN2S(=O)(=O)C3=CC=CC(=C3)O.Cl |
| Reference | <p style=”/line-height:25px/”> |
