SB 414240

• CAT Number: I009339
• CAS Number: 272104-60-6
• Molecular Formula: C33H44N4O
• Molecular Weight: 512.74
• Purity: ≥95%
• Synonyms: SB 414240; SB-414240; SB414240.;N-[(2S)-3,3-dimethylbutan-2-yl]-2-phenyl-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
• Solubility: Soluble in DMSO
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: N-[(2S)-3,3-dimethylbutan-2-yl]-2-phenyl-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
• InChI: InChI=1S/C33H44N4O/c1-24(33(2,3)4)34-32(38)30-27-15-9-10-16-29(27)35-31(25-13-7-5-8-14-25)28(30)23-36-21-17-26(18-22-36)37-19-11-6-12-20-37/h5,7-10,13-16,24,26H,6,11-12,17-23H2,1-4H3,(H,34,38)/t24-/m0/s1
• InChIKey: RTUNBOPBBCULLC-DEOSSOPVSA-N
• SMILES: O=C(C1=C(CN2CCC(N3CCCCC3)CC2)C(C4=CC=CC=C4)=NC5=CC=CC=C15)N[C@H](C(C)(C)C)C

SB 414240(CAT: I009339) is a selective and potent antagonist of the neuropeptide Y receptor Y5 (NPY Y5). This receptor is implicated in the regulation of food intake and energy homeostasis. By blocking Y5 receptor activity, SB 414240 has been investigated for its potential to reduce appetite and contribute to anti-obesity treatments. Additionally, it serves as a research tool to explore the role of NPY Y5 in metabolic disorders, stress responses, and neuroendocrine regulation. SB 414240 is a valuable compound for studying NPY-mediated signaling pathways and their therapeutic potential in obesity and related conditions.