For research use only. Not for therapeutic Use.
SB-611812 is a urotensin II receptor (UTR) antagonist with the potential in the research of cardiovascular disease[1][2].
| Catalog Number | I009345 |
| CAS Number | 345892-71-9 |
| Synonyms | 2,6-dichloro-N-[4-chloro-3-[2-(dimethylamino)ethoxy]phenyl]-4-(trifluoromethyl)benzenesulfonamide |
| Molecular Formula | C17H16Cl3F3N2O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C17H16Cl3F3N2O3S/c1-25(2)5-6-28-15-9-11(3-4-12(15)18)24-29(26,27)16-13(19)7-10(8-14(16)20)17(21,22)23/h3-4,7-9,24H,5-6H2,1-2H3 |
| InChIKey | UIZHOFJFIOCYLH-UHFFFAOYSA-N |
| SMILES | CN(C)CCOC1=C(C=CC(=C1)NS(=O)(=O)C2=C(C=C(C=C2Cl)C(F)(F)F)Cl)Cl |
| Reference | [1]. Rakowski E, et al. A role for urotensin II in restenosis following balloon angioplasty: use of a selective UT receptor blocker. J Mol Cell Cardiol. 2005 Nov;39(5):785-91. [2]. Cosenzi A. Non peptidic urotensin II antagonists: perspectives for a new class of drugs. Cardiovasc Hematol Agents Med Chem. 2008 Apr;6(2):80-91. |
