For research use only. Not for therapeutic Use.
Selective NOP receptor antagonist
| Catalog Number | I012241 |
| CAS Number | 371980-98-2 |
| Molecular Formula | C24H29Cl2NO.HCl |
| Purity | ≥95% |
| IUPAC Name | (5S,7S)-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-1-methyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol;hydrochloride |
| InChI | InChI=1S/C24H29Cl2NO.ClH/c1-16-4-2-5-20-19(16)9-8-17(14-23(20)28)15-27-12-10-18(11-13-27)24-21(25)6-3-7-22(24)26;/h2-7,17-18,23,28H,8-15H2,1H3;1H/t17-,23-;/m0./s1 |
| SMILES | CC1=C2CC[C@@H](C[C@@H](C2=CC=C1)O)CN3CCC(CC3)C4=C(C=CC=C4Cl)Cl.Cl |
| Reference | Anna Rizzi et al. Pharmacological Characterization of the Nociceptin/Orphanin FQ Receptor Antagonist SB-612111: In Vivo Studies. J. Pharmacol. Exp. Ther. 2007, 321(3), 968-974.
B Spagnolo et al. Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111: in vitro studies. J Pharmacol. Exp. Ther. 2007, 321(3), 961-7.
PF Zaratin et al. Modification of nociception and morphine tolerance by the selective opiate receptor-like orphan receptor antagonist SB-612111. J. Pharmacol. Exp. Ther. 2004, 308(2), 454-61. |
