For research use only. Not for therapeutic Use.
SB-743921 (SB-921) is an inhibitor of Kinesin Spindle Protein (KSP), a mitotic protein essential for cell cycle control and motility. It functions by selectively targeting rapidly dividing cells and disrupting spindle formation during cell division, leading to G2/M phase arrest and ultimately causing cell death. It also inhibits proliferation and induces apoptosis in diffuse large B-cell lymphoma (DLBCL) cell lines.
| Catalog Number | I009363 |
| CAS Number | 618430-39-0 |
| Molecular Formula | C31H33ClN2O3.ClH |
| Purity | ≥95% |
| Reference | [1] Bongero D, et al. Leuk Lymphoma. 2015;56(10):2945-52. |
