SBP-3264

• CAT Number: I045326
• CAS Number: 2869148-13-8
• Molecular Formula: C19H20ClN5O
• Molecular Weight: 369.85
• Purity: ≥95%
• Synonyms: N-[1-[5-(3-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]piperidin-4-yl]acetamide
• InChI: InChI=1S/C19H20ClN5O/c1-12(26)24-15-5-7-25(8-6-15)19-17-16(10-21-18(17)22-11-23-19)13-3-2-4-14(20)9-13/h2-4,9-11,15H,5-8H2,1H3,(H,24,26)(H,21,22,23)
• InChIKey: AYRVYPOFYQSRNH-UHFFFAOYSA-N
• SMILES: CC(=O)NC1CCN(CC1)C2=NC=NC3=C2C(=CN3)C4=CC(=CC=C4)Cl

SBP-3264 is a valuable chemical probe for understanding the roles of STK3 and STK4 in acute myeloid leukemia (AML).

Reference

[1]. Bata N, et al. Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia. J Med Chem. 2021 Nov 22.
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